Hubungan Pengetahuan dan Kesadaran terhadap COVID-19 dengan Asupan Vitamin D dan Seng pada Mahasiswa Kedokteran UNS
DOI:
https://doi.org/10.20961/plexus.v2i2.615Abstract
Pendahuluan: COVID-19 telah ditetapkan sebagai pandemi global oleh World Health Organization (WHO). Pengetahuan dan kesadaran yang berhubungan dengan COVID-19 pada mahasiswa khususnya mahasiswa kedokteran sudah baik. Penelitian telah membuktikan vitamin D berperan sebagai imunomodulator sistem kekebalan tubuh dan seng yang memiliki peran dalam kekebalan antivirus termasuk coronavirus. Oleh sebab itu, penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dan kesadaran terhadap COVID-19 dengan asupan vitamin D dan seng pada mahasiswa kedokteran Universitas Sebelas Maret.
Metode: Penelitian yang digunakan adalah observasional analitik dengan pendekatan cross-sectional. Subjek penelitian ini adalah mahasiswa kedokteran UNS dengan kriteria inklusi. Subjek dipilih dengan metode simple random sampling dengan jumlah 91 responden yang memenuhi kriteria inklusi. Data dianalisis dengan metode Spearman.
Hasil: Hasil penelitian didapatkan hubungan lemah dan tidak signifikan antara pengetahuan dan kesadaran terhadap COVID-19 dengan asupan vitamin D dan seng. Hubungan Pengetahuan dan kesadaran terhadap asupan vitamin D memiliki koefisien masing-masing r = 0.257 dan r = 0.129. Hubungan pengetahuan dan kesadaran terhadap asupan seng memiliki koefisien masing-masing r = 0.057 dan r = 0.112.
Kesimpulan: Didapatkan hasil berupa hubungan lemah dan tidak signifikan antara pengetahuan dan kesadaran terhadap COVID-19 dengan asupan vitamin D dan seng pada mahasiswa kedokteran Universitas Sebelas Maret
Keywords:
COVID-19, pengetahuan, kesadaran, vitamin D, sengReferences
Adli, I., Widyahening, I. S., Lazarus, G., Phowira, J., Baihaqi, L. A., & Ariffandi, B., et al. (2022). Knowledge, attitude, and practice related to the COVID-19 pandemic among undergraduate medical students in Indonesia: A nationwide cross-sectional study. PLOS ONE, 17(1), e0262827. https://doi.org/10.1371/journal.pone.0262827
Asl, S. H., Nikfarjam, S., Majidi Zolbanin, N., Nassiri, R., & Jafari, R. (2021). Immunopharmacological perspective on zinc in SARS-CoV-2 infection. International Immunopharmacology, 96, 107630. https://doi.org/10.1016/j.intimp.2021.107630
Bergman, P., Lindh, Å. U., Björkhem-Bergman, L., & Lindh, J. D. (2013). Vitamin D and Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. PLoS ONE, 8(6), e65835. https://doi.org/10.1371/journal.pone.0065835
Biglari, H., Hami, M., Yari, A., Poursadeghiyan, M., & Farrokhi, M. (2017). Awareness of Medical Students of Gonabad University About Nutrition and Food Preservation in Disasters. Health in Emergencies and Disasters Quarterly, 2(3), 133–138. https://doi.org/10.18869/nrip.hdq.2.3.133
Grant, W., Lahore, H., McDonnell, S., Baggerly, C., French, C., & Aliano, J., et al. (2020). Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients, 12(4), 988. https://doi.org/10.3390/nu12040988
Gugus Tugas Percepatan Penanganan COVID-19. (2021, Jun 14). Situasi Virus Covid di Indonesia. https://covid19.go.id/
Hojyo, S., & Fukada, T. (2016). Roles of Zinc Signaling in the Immune System. Journal of Immunology Research, 2016, 1–21. https://doi.org/10.1155/2016/6762343
Im, J. H., Je, Y. S., Baek, J., Chung, M.-H., Kwon, H. Y., & Lee, J.-S. (2020). Nutritional status of patients with COVID-19. International Journal of Infectious Diseases, 100, 390–393. https://doi.org/10.1016/j.ijid.2020.08.018
Jiang, R.-D., Liu, M.-Q., Chen, Y., Shan, C., & Zhou, Y.-W., et al. (2020). Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2. Cell, 182(1), 50-58.e8. https://doi.org/10.1016/j.cell.2020.05.027
Kaushik, N., Subramani, C., Anang, S., Muthumohan, R., Shalimar, & Nayak, B., et al. (2017). Zinc Salts Block Hepatitis E Virus Replication by Inhibiting the Activity of Viral RNA-Dependent RNA Polymerase. Journal of Virology, 91(21). https://doi.org/10.1128/JVI.00754-17
Kongsbak, M., Levring, T. B., Geisler, C., & von Essen, M. R. (2013). The Vitamin D Receptor and T Cell Function. Frontiers in Immunology, 4. https://doi.org/10.3389/fimmu.2013.00148
L Bishop, E., Ismailova, A., Dimeloe, S., Hewison, M., & White, J. H. (2021). Vitamin D and Immune Regulation: Antibacterial, Antiviral, Anti‐Inflammatory. JBMR Plus, 5(1). https://doi.org/10.1002/jbm4.10405
Labban, L., Thallaj, N., & Labban, A. (2020). Assessing the Level of Awareness and Knowledge of COVID 19 Pandemic among Syrians. Archives of Medicine, 12(3). https://doi.org/10.36648/1989-5216.12.3.309
Li, L., Huang, T., Wang, Y., Wang, Z., Liang, Y., & Huang, T., et al. (2020). COVID‐19 patients’ clinical characteristics, discharge rate, and fatality rate of meta‐analysis. Journal of Medical Virology, 92(6), 577–583. https://doi.org/10.1002/jmv.25757
Liu, S., Cao, X., Guo, H., & Wei, W. (2021). Zinc Influx Restricts Enterovirus D68 Replication. Frontiers in Microbiology, 12. https://doi.org/10.3389/fmicb.2021.748546
Maggini, S., Pierre, A., & Calder, P. (2018). Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients, 10(10), 1531. https://doi.org/10.3390/nu10101531
Mayor-Ibarguren, A., Busca-Arenzana, C., & Robles-Marhuenda, Á. (2020). A Hypothesis for the Possible Role of Zinc in the Immunological Pathways Related to COVID-19 Infection. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.01736
Read, S. A., Obeid, S., Ahlenstiel, C., & Ahlenstiel, G. (2019). The Role of Zinc in Antiviral Immunity. Advances in Nutrition, 10(4), 696–710. https://doi.org/10.1093/advances/nmz013
Sassi, F., Tamone, C., & D’Amelio, P. (2018). Vitamin D: Nutrient, Hormone, and Immunomodulator. Nutrients, 10(11), 1656. https://doi.org/10.3390/nu10111656
Sondakh, J. J. S., Warastuti, W., Susatia, B., Wildan, Moh., Sunindya, B. R., & Budiyanto, Moch. A. K., et al. (2022). Indonesia medical students’ knowledge, attitudes, and practices toward COVID-19. Heliyon, 8(1), e08686. https://doi.org/10.1016/j.heliyon.2021.e08686
Taghrir, M. H., Borazjani, R., & Shiraly, R. (2020). COVID-19 and Iranian Medical Students; A Survey on Their Related-Knowledge, Preventive Behaviors and Risk Perception. Archives of Iranian Medicine, 23(4), 249–254. https://doi.org/10.34172/aim.2020.06
Wan, Y., Shang, J., Graham, R., Baric, R. S., & Li, F. (2020). Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus. Journal of Virology, 94(7), Article e00127–20 https://doi.org/10.1128/JVI.00127-20
World Health Organization. (2020a, Jul 7). Coronavirus Disease (COVID-19). https://covid19.who.int/
World Health Organization. (2020b, Jul 7). Update on coronavirus disease in Indonesia. https://www.who.int/indonesia/news/novel-coronavirus
Zein, M. M., Mahmoud, A. T., el Hawary, A. S., & Hegazy, N. (2021). Cardiovascular Diseases Healthy Diet Related Knowledge among a Sample of the General Population in Egypt. Open Access Macedonian Journal of Medical Sciences, 9(B), 1764–1771. https://doi.org/10.3889/oamjms.2021.7541
Zhang, L., Zhu, F., Xie, L., Wang, C., Wang, J., & Chen, R., et al. (2020). Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China. Annals of Oncology, 31(7), 894–901. https://doi.org/10.1016/j.annonc.2020.03.296
Zou, X., Chen, K., Zou, J., Han, P., Hao, J., & Han, Z. (2020). Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Frontiers of Medicine, 14(2), 185–192. https://doi.org/10.1007/s11684-020-0754-0
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