Uji Aktivitas Antibakteri Sediaan Lulur Ekstrak Etanol Kunyit Terhadap Bakteri Staphylococcus Aureus ATCC 25923
DOI:
https://doi.org/10.20961/jaht.v1i1.315Keywords:
bodyscrub, Staphylococcus aureus, turmericAbstract
Staphylococcus aureus is a normal skin flora that can cause several skin diseases such as ulcers, acne, pneumonia, meningitis, and arthritis. Turmeric contains curcumin which has antibacterial activity. The addition of turmeric extract to the scrub formula can inhibit the activity of S. aureus. The purpose of this study was to determine the effect of turmeric ethanol extract scrub preparations against S. aureus. The research was conducted experimentally in the laboratory. The extraction process is carried out by soxhletation. Antibacterial activity test was carried out using the scrub well method with various formulas of 1%; 3%; 5%, positive control, and negative control. The results showed that formula 3 with a concentration of 5% turmeric ethanol extract showed the highest antibacterial activity against S. aureus with an inhibition zone of 10.9 mm.
References
Dimpudus SA. Formulasi Sediaan Sabun Cair Antiseptik Ekstrak Etanol Bunga Pacar Air (Impatiens Balsamina L.) Dan Uji Efektivitasnya Terhadap Bakteri Staphylococcus aureus Secara In Vitro. Pharmacon. 2017;6(3).
Goel A, Kunnumakkara AB, Aggarwal BB. Curcumin as “Curecumin”: from kitchen to clinic. Biochem Pharmacol. 2008 Feb 15;75(4):787–809.
Gupta SC, Prasad S, Kim JH, Patchva S, Webb LJ, Priyadarsini IK, et al. Multitargeting by curcumin as revealed by molecular interaction studies. Nat Prod Rep. 2011 Nov;28(12):1937–55.
Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Multiple Biological Activities Of Curcumin: A Short Review. Life Sci. 2006 Mar 27;78(18):2081–7.
Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A Review On Antibacterial, Antiviral, And Antifungal Activity Of Curcumin. Biomed Res Int. 2014;2014:186864.
Schraufstatter E, Bernt H. Antibacterial Action Of Curcumin And Related Compounds. Nature. 2022;164(4167):456–7.
Pangemanan A, Fatimawali, Budiarso F. Uji Daya Hambat Ekstrak Rimpang Kunyit (Curcuma Longa) Terhadap Pertumbuhan Bakteri Staphylococcus aureus Dan Pseudomonas sp. Jurnal e-Biomedik. 2016;4(1):81–5.
Kumara IN, Pradnyani IGAS, Sidiarta IGAFN. Uji Efektivitas Ekstrak Kunyit (Curcuma Longa) Terhadap Daya Hambat Pertumbuhan Bakteri Streptococcus Mutans. Intisari Sains Medis. 2019;10(3):462–7.
Yuliati Y. Uji Efektivitas Ekstrak Kunyit sebagai Antibakteri dalam Pertumbuhan Bacillus sp dan Shigella dysentriae secara In Vitro. JPM [Internet]. 2017 [cited 2022 Aug 5];10(1). Available from: https://ejournal.upnvj.ac.id/index.php/JPM/article/view/11
Prabandani R, Suherman H. Formulasi Sediaan Lulur Pencerah dan Penghalus Kulit dari Kunyit (Curcuma longa Linn). Viva Medika. 2018;
Tyagi P, Singh M, Kumari H, Kumari A, Mukhopadhyay K. Bactericidal Activity Of Curcumin I Is Associated With Damaging Of Bacterial Membrane. PLoS One. 2015;10(3):e0121313.
Tong SYC, Davis JS, Eichenberger E, Holland TL, Fowler VG. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, And Management. Clin Microbiol Rev. 2015 Jul;28(3):603–61.
Cahyani CI, Safitri CINH. Formulasi dan Uji Mutu Fisik Ekstrak Temu Ireng (Curcuma Aeruginosa Robx) sebagai Lulur Antioksidan. In Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek). 2021;
Isfianti DE, Pritasari OK. Pemanfaatan limbah kulit buah jeruk nipis (Citrus Aurantifolia) Dan Daun Kelor (Moringa Oleifera Lamk) Untuk Pembuatan Lulur Tradisional Sebagai Alternatif “Green Cosmetics.” Jurnal Tata Rias. 2018;7(2).
Cobra LS, Amini HW, Putri EA. Skrining Fitokimia Ekstrak Sokhletasi Rimpang Kunyit (Curcuma Longa) dengan Pelarut Etanol 96%. Jurnal Ilmiah Kesehatan Karya Putra Bangsa. 2019;1(1):12–7.
Kusuma IM, Aunillah S, Djuhariah YS. Formulasi Krim Lulur Scrub dari Ekstrak Etanol Ubi Jalar Ungu (Ipomoea Batatas (L.) Lam) dan Serbuk Beras Putih (Oryza Sativa L.). Jurnal Farmasi Udayana. 2021;177–83.
Astari SM, Rialita A, Mahyarudin M. Aktivitas Antibakteri Isolat Bakteri Endofit Tanaman Kunyit (Curcuma Longa L.) Terhadap Pertumbuhan Staphylococcus Aureus. Jurnal Fitofarmaka Indonesia. 2021;8(2):9–16.
Teow SY, Liew K, Ali SA, Khoo ASB, Peh SC. Antibacterial Action of Curcumin Against Staphylococcus Aureus: A Brief Review. J Trop Med. 2016;2016:2853045.
Rawung FT, Karauwan FA, Pareta DN, Palandi RR. Uji Aktivitas Antibakteri Formulasi Sediaan Salep Ekstrak Daun Krisan Chrysanthemum morifolium Terhadap Bakteri Staphylococcus Aureus. Biofarmasetikal Tropis. 2020;3(2):8–16