Hubungan Imunisasi BCG dengan Tuberkulosis Paru pada Anak Balita di RSUD Dr.Moewardi
DOI:
https://doi.org/10.20961/plexus.v1i1.15Abstract
Background: Tuberculosis is still one of the main threats to public health as a cause of death from infectious diseases. One of the preventive efforts to prevent tuberculosis is the BCG immunization program, but the effectiveness of BCG immunization has decreased and the results differ in various research locations so it needs to be reviewed. This study aims to determine the relationship between BCG immunization and the incidence of pulmonary tuberculosis in children under five
Methods: This research is an analytic observational design with a case control study conducted at RSUD Dr. Moewardi. Respondents in this study were divided into 2 groups, namely 30 case samples (pulmonary TB) and 30 control samples (non-pulmonary TB) where sampling was done by purposive sampling method. Samples were obtained from patient medical record data in the 2017-2019 period and then processed using SPSS 26 software
Results: Based on the results of the bivariate analysis using the Fisher's Exact test, the correlation between phi (ρ) of 0.612 (α = 0.05) showed that there was no significant relationship between BCG immunization and pulmonary tuberculosis in children under five at Dr. Moewardi.
Conclusion: There is no significant relationship between the provision of BCG immunization with the incidence of pulmonary tuberculosis in children under five at RSUD Dr. Moewardi Surakarta.
References
Sulis G, Roggi A, Matteelli A, Raviglione MC (2014). Tuberculosis: Epidemiology and control. Mediterranean journal of hematology and infectious diseases, 6 (1).
Khan MK, Islam MN, Ferdous J, dan Alam MM (2019). An Overview on Epidemiology of Tuberculosis. Mymensingh medical journal: MMJ, 28 (1): 259-266.
Kementrian Kesehatan RI (2018). Pusat data dan informasi Kemenkes RI 2017. Jakarta: Kementrian Kesehatan RI
Dinas Kesehatan Provinsi Jawa Tengah (2019). Profil kesehatan Provinsi Jawa Tengah tahun 2018. Semarang: Dinas Kesehatan Provinsi Jawa Tengah
Bamford A, Dixon G, Klein N, Marks SD, Ritz N, Welch SB, dan Tebruegge M (2020). Preventing tuberculosis in paediatric kidney transplant recipients: is there a role for BCG immunisation pre-transplantation in low tuberculosis incidence countries?. Pediatric Nephrology, 1-9.
Ritz N, Dutta B, Donath S, Casalaz D, Connell TG, Tebruegge M, dan Curtis N (2012). The influence of bacille Calmette-Guerin vaccine strain on the immune response against tuberculosis: a randomized trial. American journal of respiratory and critical care medicine, 185 (2): 213-222.
Luca S, Mihaescu T (2013). History of BCG vaccine. Maedica, 8 (1): 53-58.
Jafri Y & Sesrinayenti S (2018). STATUS IMUNISASI BCG DENGAN KEJADIAN TUBERKULOSIS PARU PADA ANAK USIA BALITA. In PROSIDING SEMINAR KESEHATAN PERINTIS 1 (2): 54-54.
Korua ES, Kapantow NH, dan Kawatu PA (2014). Hubungan Antara Umur, Jenis Kelamin dan Kepadatan Hunian dengan Kejadian TB Paru pada Pasien Rawat Jalan di Rumah Sakit Umum Daerah Noongan. Manado: Fakultas Kesehatan Masyarakat Universitas Sam Ratulangi.
Salsabilla A, dan Rezania Asyfiradayati SKM (2020). Hubungan Antara Status Imunisasi BCG dan Riwayat Kontak Serumah dengan Kejadian Tuberkulosis Paru Anak di Wilayah DKK Surakarta (Doctoral dissertation, Universitas Muhammadiyah Surakarta).
Wangsa DC (2015). Hubungan imunisasi BCG dengan kejadian tuberculosis paru pada balita. SKRIPSI-2015.
Tanner R, Villarreal-Ramos B, Vordermeier HM, McShane H (2019). The humoral immune response to BCG vaccination. Frontiers in immunology, 10, 1317.
Voysey M, Kelly DF, Fanshawe TR, Sadarangani M, O’Brien KL, Perera R, Pollard AJ et al (2017). The influence of maternally derived antibody and infant age at vaccination on infant vaccine responses: an individual participant meta-analysis. JAMA pediatrics, 171(7): 637-646.
Kementrian Kesehatan RI (2014). Buku Ajar Imunisasi 2017. Jakarta: Kementrian Kesehatan RI.
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