Profil Kliniko Patologi Lesi Granulomatosa Ekstra Paru di RSUD Raden Mattaher Jambi
DOI:
https://doi.org/10.20961/plexus.v5i5.3095Keywords:
Tuberkulosis, Tuberkulosis Ekstra Paru, Karakteristik Klinis, Gambaran Patologi, Lesi GranulomatosaAbstract
Pendahuluan: Indonesia menempati posisi kedua secara global dalam beban kasus tuberkulosis (TB). Informasi mengenai manifestasi lesi granulomatosa pada TB ekstra paru (TBEP) masih terbatas, sehingga menimbulkan tantangan diagnostik. Penelitian ini bertujuan mendeskripsikan distribusi dan karakteristik lesi granulomatosa ekstra paru di RSUD Raden Mattaher Jambi.
Metode: Penelitian deskriptif retrospektif ini menggunakan data rekam medis dan arsip patologi pasien di RSUD Raden Mattaher Jambi periode 2021–2024. Sampel dipilih menggunakan teknik total sampling berdasarkan kriteria inklusi dan eksklusi.
Hasil: Sebanyak 122 pasien dengan lesi granulomatosa ekstra paru diikutsertakan. Mayoritas pasien berusia >15 tahun (73,8%), perempuan (54,1%), tidak merokok (93,4%), dan memiliki status gizi underweight atau normal (masing-masing 41%). Lokasi lesi terbanyak ditemukan pada saluran cerna (44,3%). Gambaran mikroskopis granulomatosa ditemukan pada 79,5% kasus, sedangkan diagnosis definitif patologi anatomi (PA) menunjukkan tuberkulosis pada 60,7% kasus. Berdasarkan profil mikroskopis dan status diagnosis, ditemukan TBEP dengan gambaran granulomatosa pada 58 pasien (47,5%), suspek TB dengan gambaran granulomatosa pada 39 pasien (32%), TBEP dengan gambaran tuberkel klasik pada 17 pasien (13,9%), serta suspek TB dengan gambaran tuberkel klasik pada 8 pasien (6,6%).
Kesimpulan: Lesi granulomatosa ekstra paru didominasi pasien dewasa, perempuan, dan berlokasi di saluran cerna. Gambaran granulomatosa merupakan temuan mikroskopis terbanyak. Meskipun diagnosis definitif TB ditegakkan pada 60,7% kasus, proporsi gambaran granulomatosa
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Copyright (c) 2026 Dhea Fadila Wijaya, Fairuz Quzwain , Armaidi Darmawan , Hasna Dewi , Citra Maharani
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