CLINICAL AND SOCIODEMOGRAPHIC FACTORS ASSOCIATED WITH QUALITY OF LIFE IN EPILEPSY PATIENTS AT DORIS SYLVANUS HOSPITAL PALANGKA RAYA

Authors

  • Ariqah Ghaniyah Lembah Faculty of Medicine, Universitas Palangka Raya, Palangka Raya, Indonesia
  • Ranintha Br. Surbakti Department of Neurology, Faculty of Medicine, Universitas Palangka Raya, Palangka Raya, Indonesia
  • Ravenalla Abdurrahman Al Hakim Sampurna Putra Solihin Department of Public Health, Faculty of Medicine, Universitas Palangka Raya, Palangka Raya, Indonesia
  • Farah Fauziyah Radhiyatulqalbi Ahmad Department of Physiology, Faculty of Medicine, Universitas Palangka Raya, Palangka Raya, Indonesia
  • Nuch Sabunga Department of THT-KL, Dr. Doris Sylvanus Hospital, Palangka Raya, Palangka Raya, Indonesia

DOI:

https://doi.org/10.20961/magnaneurologica.v4i2.2986

Keywords:

clinical factors, epilepsy, QOLIE-31, quality of life, sociodemographic factors

Abstract

Background: Epilepsy is a chronic neurological disorder that affects patients' physical, psychological, and social aspects, influencing their quality of life (QoL). Identifying clinical and sociodemographic factors related to QoL is essential for comprehensive management.

Objective: To analyze the relationship between clinical and sociodemographic factors and the quality of life of epilepsy patients at the Neurology Polyclinic of RSUD dr. Doris Sylvanus Palangka Raya.

Methods: This analytical observational study with a cross-sectional design involved 53 respondents selected through consecutive sampling. Data were collected using the QOLIE-31 to assess QoL, the MARS-5 to assess medication adherence, the MSPSS to assess social support, and a validated knowledge questionnaire. Relationships between variables were analyzed using the Spearman correlation test with a significance level of p < 0.05.

Results: Most respondents were adults aged 19-45 years (83.0%), male (52.8%), and had secondary education. The mean QOLIE-31 score was 52.24 (SD 20.02), indicating moderate QoL. Significant correlations were found between seizure frequency (r = -0.506; p < 0.001), comorbidity (r = -0.368; p = 0.007), medication adherence (r = 0.483; p < 0.001), social support (r = 0.396; p = 0.004), and knowledge level (r = 0.587; p < 0.001) with QoL. Age at diagnosis (p = 0.119) and epilepsy duration (p = 0.397) were not significantly related.

Conclusion: Quality of life in epilepsy patients is significantly associated with seizure frequency, comorbidity, medication adherence, social support, and knowledge level. Improving adherence and psychosocial support can enhance patients' overall well-being.

References

1. Rizkiyah R, Pradini George N. Hubungan Edukasi Kebersihan Mulut dengan Perilaku Menyikat Gigi pada Anak Usia Sekolah. J Gema Kesehat; 2022. 10(2):45–52. Retrieved on October 10, 2025. Available from: http://jurnalpoltekkesjayapura.com/index.php/gemakes/article/view/

2. Thomas JA, Ditchman NM, Guidotti Breting L, Narayanan J. Quality of life in people with epilepsy: The associations of anti-seizure medications and biopsychosocial variables. Epilepsy Behav; 2024. 152:109664. DOI: 10.1016/j.yebeh.2024.109664

3. World Health Organization. Epilepsy; 2024. Retrieved on October 10, 2025. Available from: https://www.who.int/news-room/fact-sheets/detail/epilepsy

4. World Health Organization. Epilepsy: A Public Health Imperative. Geneva: WHO; 2019. Retrieved on October 10, 2025. Available from: https://www.who.int/publications/i/item/epilepsy-a-public-health-imperative

5. Bala A, Olejnik A, Kułak M, Rysz A, Dziedzic T, Nowak A, et al. Determinants of the Quality of Life in Patients with Drug-Resistant Temporal Lobe Epilepsy: A Comparison of the Results before and after Surgery. Brain Sci; 2024. 14(3):241. DOI: 10.3390/brainsci14030241

6. Oktavia N, Latifah H, Septiyani R. Faktor-Faktor yang Mempengaruhi Kualitas Hidup Pasien Epilepsi. J Ilm Pharm; 2023. 10(1):99–108. Retrieved on October 10, 2025. Available from: http://journal.uml.ac.id/JIPHAR/article/view/

7. Andualem F, Melkam M, Tadesse G, Nakie G, Tinsae T, Fentahun S, et al. Quality of life and associated factors among people with epilepsy in Ethiopia: a systematic review and meta-analysis. BMC Public Health; 2024. 24(1). DOI: 10.1186/s12889-024-19018-3

8. World Health Organization. Epilepsy in the South-East Asia Region: Regional Report 2023. New Delhi: WHO SEARO; 2023. Retrieved on October 10, 2025. Available from: https://iris.who.int/handle/10665/375924

9. Kementerian Kesehatan Republik Indonesia. Mari Kenali Gejala Epilepsi; 2022. Retrieved on October 10, 2025. Available from: https://keslan.kemkes.go.id/view_artikel/71/mari-kenali-gejala-epilepsi

10. Reijneveld JC, Thijs RD, van Thuijl HF, Appelhof BA, Taphoorn MJB, Koekkoek JAF, et al. Clinical outcome assessment in patients with epilepsy: The value of health-related quality of life measurements. Epilepsy Res; 2024. 200:107310. DOI: 10.1016/j.eplepsyres.2024.107310

11. Angelia MA. Hubungan Lama Pasien Mengidap Penyakit Parkinson dan Tingkat Pengetahuan Caregivers dengan Kualitas Hidupnya di Poliklinik Neurologi RSUD dr. Doris Sylvanus [Undergraduate Thesis]. Palangkaraya: Fakultas Kedokteran Universitas Palangkaraya; 2024. Retrieved on October 10, 2025. Available from: https://repository.upr.ac.id/

12. Perhimpunan Dokter Spesialis Saraf Indonesia (PERDOSSI). Epilepsi. In: Kurniawan M, Ganiem RA, Wiratman W, editors. Pedoman Praktik Klinis Neurologi 2023. Jakarta: PERDOSSI; 2023. p.1–8.

13. Kementerian Kesehatan Republik Indonesia. Riset Kesehatan Dasar 2022. Jakarta: Badan Litbangkes; 2022. Retrieved on October 10, 2025. Available from: https://www.badankebijakan.kemkes.go.id/hasil-utama-riskesdas-2022/

14. Puspitasari AF. Hubungan Umur Pertama Terjadinya Bangkitan Epilepsi dengan Skor Kualitas Hidup Pasien Epilepsi; 2020. Retrieved on October 10, 2025. Available from: https://repository.unair.ac.id/

15. Siebenbrodt K, Willems LM, von Podewils F, Mross PM, Strüber M, Langenbruch L, et al. Determinants of quality of life in adults with epilepsy: a multicenter, cross-sectional study from Germany. Neurol Res Pract; 2023. 5(1):41. DOI: 10.1186/s42466-023-00265-5

16. Tu H, Gong G, Zhang S, Fu Y, Wang T, Chu Q, et al. The association between illness perception and quality of life among Chinese adults with epilepsy: The mediating role of coping style. Epilepsy Behav; 2022. 130:108677. DOI: 10.1016/j.yebeh.2022.108677

17. WenJing G, JiaFeng W. Living With Epilepsy the Experiences of Adult People: A Descriptive Literature Review [Dissertation]; 2023. DOI: diva2:1759185

18. Yesuf W, Hiko D, Alemayehu E, Kusheta S, Shita A, Beyene M. Health-related quality of life in epilepsy and its associated factors among adult patients with epilepsy attending Mizan Tepi University Teaching Hospital, Southwest Ethiopia: a cross-sectional study. BMJ Open; 2024. 14(1):e079165. DOI: 10.1136/bmjopen-2023-079165

19. Kassie AM, Abate BB, Kassaw MW, Getie A, Wondmieneh A, Tegegne KM, et al. Quality of life and its associated factors among epileptic patients attending public hospitals in North Wollo Zone, Northeast Ethiopia: A cross-sectional study. PLoS One; 2021. 16(2):e0247336. DOI: 10.1371/journal.pone.0247336

20. Pallavi, Verma R, Gupta R, Shafqat N, Phalswal U. A study to assess medication adherence and quality of life among epilepsy patients seeking treatment at AIIMS Bhopal. J Fam Med Prim Care; 2024. 13(8):3292–7. DOI: 10.4103/jfmpc.jfmpc_155_24

21. Osman T, Jaralla M, Biad T, Abd M, Aouda Z, Hashem K, et al. Unveiling the Hidden Burden: Medication-Related Problems in Epilepsy and Their Impact on Seizure Control & Quality of Life. J Neonatal Surg; 2025. DOI: 10.52783/jns.v14.1979

22. Ernawati I, Islamiyah WR. Korelasi Tingkat Kepatuhan Konsumsi Obat Antiepilepsi Menggunakan Kuesioner MGLS (Morisky, Green, Levine Adherence Scale) dengan Frekwensi Kejang Pasien Epilepsi. J Farm Udayana; 2021. 10(2):121–8. DOI: 10.24843/JFU.2021.v10.i02.p02

23. Demir TG, Havlioğlu S. Quality of Life and Employment Among Patients with Epilepsy. Genel Tip Derg; 2024. 34(4):559–65. DOI: 10.54005/geneltip.1474401

24. Mula M, Kanner AM, Jetté N, Sander JW. Psychiatric Comorbidities in People With Epilepsy. Neurol Clin Pract; 2021. 11(2):E112–20. DOI: 10.1212/CPJ.0000000000000874

25. Unalan D, Soyuer F, Basturk M, Ersoy AO, Elmali F, Ozturk A. Perceived social support and coping strategies in patients with depression: A longitudinal study. Int J Soc Psychiatry; 2025. 20(1):17–26. DOI: 10.1177/00207640251353680

26. Tedrus GMAS, Leandro-Merhi VA, Etchegaray A, Randi YM. Family support in adults with epilepsy. Arq Neuropsiquiatr; 2023. 81(11):956–60. DOI: 10.1055/s-0043-1777004

Downloads

Published

2026-07-15

Issue

Section

Original Research

How to Cite

CLINICAL AND SOCIODEMOGRAPHIC FACTORS ASSOCIATED WITH QUALITY OF LIFE IN EPILEPSY PATIENTS AT DORIS SYLVANUS HOSPITAL PALANGKA RAYA. (2026). Magna Neurologica, 4(2), 98-102. https://doi.org/10.20961/magnaneurologica.v4i2.2986

Similar Articles

1-10 of 52

You may also start an advanced similarity search for this article.